Central Research Instrumentation Facility

CentralResearch Instrumentation Facilityalso called as Corelabhouses specialized high end equipment for common usage of scientists, scholars and students at Vision Research foundation. Ensuring the availability of various sophisticated instruments to the researchers and providing quality research solutions for the development of high standards towards Ophthalmic Research is the thriving aim of this Facility in accordance with the mission of the Organization.

The purpose of Core laboratory is to provide organized infrastructurewith high end technology, expensive instrumentation that cannot readily be accomplished in an individual laboratory. Not restricted to this the facility also helps in

• Experimental planning, sample processing and data analysis.


• Knowledge sharing by constant interaction with all the scientists, thereby increasing efficiency in research progressively


• Giving hands on training on new technologiesto the scientists and students from all other laboratories


• Conducting participatory lectures, demonstrations and presentations about new technologiesintroduced in the field of biological sciences, to keep scientists and students updated with the technological advances in the research field


• Constantly upgrading the facility with the addition of new instruments and maintenance of the existing instruments

Personnel employed in the core laboratory are equipped withscientific and multidisciplinary expertise, to guide the researchers, in choosing the best technologies and help them design their experiments efficiently, processing the samples and data analysis. Hands-on training is also facilitated to the students so that they may use the instruments independently.

A wide spectrum of research ideas integrated with the excellent facilities atcore lab, interactive Scientists, supporting scholars, healthy and competitive atmosphere provides an excellent platform for vigorous research, and makes VRF a successful ophthalmic research organization.

Staff

Immediate Past Research Fellows

Publications

1. Lakshmi Badri, Pukhraj Rishi, Ronnie George, Nancy Isaac, Ekta Rishi. Incidence, risk factors, treatment and outcome of ocular hypertension following intravitreal steroid injections: A comparative study. Accepted for publication in the journal of Ophthalmologica.


2. C Amit, G Sathe, A Shunmugam, PK Athyala, V Ghose, S Chitipothu, et al. Graphitic Carbon Nitride Causes Widespread Global Molecular Changes in Epithelial and Fibroblast Cells., ACS omega 6 (14), 9368-9380


3. R Raguraman, S Parameswaran, JR Kanwar, M Vasudevan, S Chitipothu, et al., Gene expression profiling of tumor-stroma interactions in retinoblastoma. Experimental eye research 197, 108067


4. L Badrinarayanan, S Chitipothu, S Ramasubramanyan, S Sripriya, P Rishi, et al., Assessment of single nucleotide polymorphisms associated with steroid-induced ocular hypertension. International Journal of Ophthalmology 13 (8), 1294


5. Athyala, Prasanna Kumar; Kanwar, Jagat; Chitipothu, Srujana; Subramanian, Krishnakumar, Janakiraman, Narayanan 'Synthesis of Saporin - antibody conjugates for targeting EpCAM positive tumor cells', IET Nanobiotechnology, 2018, DOI: 10.1049/iet-nbt.2018.5222, IET Digital Library


6. Athyala, P. K., Kanwar, J. R., Chitipothu, S., Kanwar, R. K., Krishnakumar, S., Watson, J. P., & Narayanan, J. (2017). Neocarzinostatin, Aptamer Conjugates for Targeting EpCAM-positive Tumor Cells. Anticancer Research, 37(7), 3615–3629


7. Jayashree, B., Srimany, A., Jayaraman, S., Bhutra, A., Janakiraman, N., Chitipothu, S., Pradeep, T. (2016). Monitoring of changes in lipid profiles during PLK1 knockdown in cancer cells using DESI MS. Analytical and Bioanalytical Chemistry, 408(20), 5623–5632.


8. Beta, M., Chitipothu, S., Khetan, V., Biswas, J., &Krishnakumar, S. (2015). Hypermethylation of Adenomatosis Polyposis Coli-2 and its Tumor Suppressor Role in Retinoblastoma. Current Eye Research, 40(7), 719–728.

Achievements

• Student Ms. Lakshmi. Badrinarayanan has completed her Ph.D. from Anna University on 03.01.2022.
• Dr. Lakshmi. Badrinarayanan is the recipient of Swarnalatha punshi award for the best research in 2020-2021

Scientists in Core-lab also conduct active research by procuring government and non-government funded projects, and guiding students in research.

PHD students

Core facility has PHD students working in Government funded projects

Research fellows

Senior and junior research fellows conduct research in various ongoing projects

Junior scientists

Junior scientists are trained to operate independently the instruments present at the core facility, to assist the researchers and the students in running their experiments efficiently

Internship students

Short term internship is given to the students pursuing their Masters / Bachelors in the field of Biological /Life sciences, from various colleges and universities in India.

Central Research Instrumentation Facility
4th Floor, KNBIRVO block
Vision Research Foundation,
18, College Road, Nungambakkam,
Chennai - 600 006.
Phone: +91-44-28271616 , Extn: 1325
Email: corelab@snmail.org / drsrujana@snmail.org