Regarding myself, I have a broad background in infectious disease especially virological and immunological techniques which includes virus cultivation and isolation, ELISA and Flowcytometry, Cell culture techniques and molecular techniques including next generation sequencing technique. I completed my doctoral research entitled “Studies on viral Immunology and control of HIV Infections and evaluation of anti HIV properties of Camellia sinensis (Green Tea)” in addition, I actively involved in various multi-centric projects funded by, MoES (Ministry of Earth Sciences) and ICMR at the Department of Microbiology, Dr.ALM PGIBMS, University of Madras, Taramani Campus, Chennai.
After my doctoral study I joined as a Senior Research Fellow in Vision Research Foundation for the ICMR project entitled “Effect of riboflavin / UVA in treating patients with infectious keratitis: A pilot study on human subjects. This project was sucessufully completed and the publication for this work is under review. Then I turned my attention to Dengue viral research which was concluded that DENV found to cause corneal infection and serological positivity induce transmission of the virus through the cornea and it stimulates the expression of TLR4, TLR7, TLR9 and TLR10 which leads to up-regulation of innate pro-inflammatory response in the cornea. Another work on 16s Metagenomic Analysis of conjuntival samples derived from Human contact lens wearers using Ion torrent personal genome machine. This work concluded that wearing contact lens may be increased the risk for causing eye infections and also the data we found conjunctival infection not only caused by predominant species like cultivable Pseudomans and also more number of uncultivatable were found in conjunctival swab samples.
The publications related these works are mentioned below.
I developed my deep interest on basic and translation research in Virology and Immunology. I applied for SERB-National Post Doctoral Fellowship (N-PDF) related to Dengue viral research.
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Anand, Appakkudal R., Gladys Rachel, and Durgadevi Parthasarathy. "HIV proteins and endothelial dysfunction: implications in cardiovascular disease." Frontiers in Cardiovascular Medicine 5 (2018): 185.
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Janani, Madhuravasal Krishnan, Parthasarathy Durgadevi, JayavelPadmapriya, JambulingamMalathi, Lily Therese Kulandai, and HN Madhavan Rao. "First Report on Detection of Dengue Virus in the Donor Cornea." Cornea (September 2018).International.
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MuruganNandagopal; DurgadeviParthasarathy; RajeswariMahadevan; PadmapriyaJayavel; HajibNarahari Rao Madhavan; Lily Kulanthai Therese; Malathijambulingam. “Meta-genomics study among four contact lens wearers from India”.Gene reports ( June 2018).
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Parthasarathy, Durgadevi, Janani Krishnan Madhuravasal, PadmapriyaJayavel, Lily Therese Kulandai, MadhavanHajibNarahari Rao, and MalathiJambulingam. "Expression analysis of toll-like receptors of Dengue-infected cornea by real-time polymerase chain reaction." Inflammation Research (April 2018): 1-4 (International)
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Gopinath, R., P. Durgadevi, V. Gopinath, and K. Vasanthi. "Efficient diagnosis of Mycobacterium tuberculosis (MTB) infections by using membrane secretory proteins of MTB."International Journal of Biology Research (April 2016):47-52(International).
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H. Durgadevi, M. Suthandhira, O. R Krishnarajasekar, C. Chandrasekar, K. Raja, B. Rayvathy, V.Gopinath, SowmyaSwaminathan, Luke Elizabeth Hanna, S. Anbalagan, J. Sathyavathi, N. Rohan. R.Gopinath and ElanchezhiyanManickan. HAART Restore the CD4+CD25+ Regulatory T Cells (Tregs) Frequency Among HIV/AIDS Patients. British Biomedical Bulletin. 2014. 2 (2):392-405(International)..
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Rohan Narayan., Durgadevi P.,Gopinath, R.,Govindaraj K.,PadmasaniVenkat Ramanan2, Sanjeeva Reddy3, and ElanchezhiyanManickan. Is Mumps a vaccine preventable disease: Are we too gullible about MMR vaccine? Indian Journal of Applied Microbiology.2014. 17(2): pp. 15-21(national)..
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Narayan R., Durgadevi P., VenkatRamanan P., Reddy S., Manickan E. Loss of efficacy of Measles Mumps Rubella (MMR) vaccine against Mumps: A serological study. BIOINFO Vaccine Sciences. 2014. 2 (1): 014-017.(International).
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Hariharan Durgadevi, Narayan R.,Ramanan V.P., Reddy S., Manickan.E. Development of acute mumps among pediatric and adult population in spite of previous MMR vaccination. BIOINFO Vaccine Sciences. 2014. 2 (1): 007-013.(International).
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Gopinath R., Rohan N.,Durgadevi H.,Govindaraju K., ElanchezhiyanManickan. Reincarnations of Influenza Virus and Challenges with the Development of a Robust Influenza Vaccine. British Biomedical Bulletin. 2014. 2 (2): 303-315.
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Narayan R., Durgadevi P., Mythily V.B., Manickan E. Prevention of Hepatitis B virus (HBV) replication by extracts of Mimosa pudica, a unique Indian medicinal plant BIOINFO Drug targets. 2014. 2 (1): 020-023.(International).
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Suthandhira, M., H. Durgadevi, O. R. Krishnarajasekar, K. Raja, B. Rayvathy, Sowmya Swaminathan, Luke Elizabeth Hanna, S. Anbalagan, and Elanchezhiyan Manickan. "HAART restores the frequency of regulatory T cells (Tregs) among HIV/AIDS patients." BMC Infectious Diseases 14, no. S3 (2014): E1.
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S Thanigaivel, H Durgadevi, J Balasubramaniam, V Mythily and M Elanchezhiyan. Comparative evaluation of the anti-Hepatitis B virus activity of Centellaasiatica and Camellia sinensis (green tea).BMC Infectious Diseases 2014, 14(Suppl 3):P21 doi:10.1186/1471-2334-14-S3-P21.(International).
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GovindharajDeepika, HariharanDurgadevi, Rohan Narayan, MunisamySudanthira, ElanchezhiyanManickan. Anti-Herpes Simplex Viruses activity of Camellia sinensis, member of the family Theaceae (green tea).BMC Infectious Diseases 2014, 14(Suppl 3):P47.(International).
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P.Durgadevi,ShubhitaTripathi, M. Suthandira, ShusammaJadav, SmitaKulkarani, Ramesh Paranjape, Hanna Luke Elizebeth, SoumyaSwaminathan, and ElanchezhiyanManickan. Inhibition of HIV gag and virus replication by a popular beverage, Camelliasinensis (Green tea) extracts. Indian Journal of Applied Microbiology, 16: 62-70, 2013.(rnational).
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Thanigaivel S., Durgadevi H., Narayan R., Mythily V. and Manickan E. Anti Hepatitis B virus (HBV) activity of extracts of Camellia sinensis, the green tea .World Research Journal of Medicinal & Aromatic Plants, November 13, 2013; Accepted: December 12, 2013, 24 Dec 2013, Pages: 39-43.(International).
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M.Manikannan, P.Durgadevi, S.Subramaniyan, and ElanchezhiyanManickan Abundant CD-4 Th-2 Cytokine stimulation by medicinal plant PongamiapinnataLin. on Human PBMC. International Journal of Plant Physiology and Biochemistry .4(1): 20-23, 2012.(International).
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Jeevan M, Nasreen N, Dinesh S, Mythily V, Durgadevi H and ElanchezhiyanManickanAnti HBV activity of HD-03/ES, a herbal medicine by interference of HBsAg binding to its receptor.Journal of Pharmacy Research, 5(8),4348-4352, 2012.(International).
2017
Dr.Madanagopal Endowment Award for best Ph.D., THESIS entitled “Studies On Viral Immunology And Control Of HIV Infections And Evaluation Of Anti HIV Properties Of Camellia sinensis(Green Tea)” from Dr. ALM. PG. Institute of Basic Medical Sciences, University of Madras.
2018
“Smt. Sreerangamma N. Narayana & Smt. Radhamani N.Anantha” Endowment Awards for the best young Scientist working on Infectious diseases.
Dr P Durgadevi, PhD
Senior Scientist
L&T Microbiology Research Center
Vision Research Foundation,
41/18 College Road, Nungambakkam
Chennai – 600 006.
Ph: +91-(044) 28271616
Email: drdurgadevi@snmail.org